Clinically Proven to Increase Skin Barrier Repair, Function, and Density in 4 Weeks
Every product in our line delivers 3% Matrikynes® peptides for the same powerful benefits. Use individually, or layer from lightest to richest for amplified results.
Every Few Decades, a New Innovation
Disrupts the Skincare Industry
Repair and Regenerate Your Skin With the World’s First Matrix-Derived Bioactive Polypeptides
Our activity optimized formulas feature patent-pending Matrikynes® polypeptides that are naturally-derived from natural extracellular matrix and clinically-proven to:
- increase skin density
- supercharge barrier function & repair
- increase hydration
- visibly reduce fine lines & deep wrinkles
- decrease the appearance of hyperpigmentation & age spots
Results That Are Never Retouched
Representative VISIA CR photography. None of the below photographs were altered, edited, or retouched.
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Satin Finish
The Hydra Duo
$243.00
For those with combo to dry skin who prefer a plumping water-based serum and a satin finish cream.
Extra Dewy
The Lipid Duo
$244.00
For those with dry, easily dehydrated skin who love an emollient cream and active-filled facial oil.
The Complete Max Repair System
$460.00
For those who want a fully customizable routine, ideal for frequent travelers and shifting climates.
What Makes Sweet Chemistry Different
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CURRENT PRACTICES
Most cosmetic treatments that promise to “build collagen” (ablative lasers, radiofrequency microneedling, bio-stimulatory injectables, etc.) have the potential to damage your skin, and in the process, create collagen in the form of non-functioning scar tissue.
> According to a survey by The Aesthetic Society, plastic surgeons are reporting that many of these treatments can decrease skin quality/function over time and make it more difficult to perform future invasive procedures.SWEET CHEMISTRY PRODUCTS
Our products repair your skin and visibly restore dermal collagen in as soon as 4 weeks without causing damage, forming healthy looking, living tissue.
> This improves your skin quality as you age and allows you to stave off invasive procedures a little longer, should you desire them. -
Our polypeptides are not a marketing “complex”. They have been granted their own internationally recognized INCI name.
CURRENT PRACTICES
Artificial, chemically-synthesized peptides traditionally used in cosmetic formulas are singular solo performers and are thought to provide some regenerative benefits to your skin.
SWEET CHEMISTRY PRODUCTS
Sweet Chemistry formulas contain 3% Matrikynes® polypeptides derived from natural extracellular matrix.
> These proprietary polypeptides consists of over 300 natural extracellular matrix polypeptides, are highly bioavailable, and clinically proven to improve skin barrier function, skin barrier repair, skin density, skin hydration, hyperpigmentation, and global fine lines and wrinkles.
> Matrikynes® technology is also currently being used in some of the most advanced areas of biomedical research, specifically in clinical applications for organ tissue repair.
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We love telling the stories behind our formulas. Just not “ingredient stories”.
CURRENT PRACTICES
Many dermatological and botanical actives you will find in conventional cosmetic products are formulated at marketing levels, sometimes referred to as “ingredient stories”.
> This means your favorite product may only contain around 0.01% of any given active ingredient. This percentage is all it takes for an ingredient to appear in the ingredients list and be marketed to you as a “hero” ingredient. (The above percentage does not refer to milder prescription strength actives like retinoids)
SWEET CHEMISTRY PRODUCTS
We use a modern, transparent approach to formulating: All of our dermatological active ingredients are included at functional levels, with our botanical actives at a minimum of 1% each. In our ingredient list, we’re also always transparent about our 1% line.
> For our Elasticity Reinforcing Cream, this means we formulate using 30% less water with antioxidants and actives making up 45% of our emulsion.
> For our Reparative Oil Serum Infusion, it means you’re getting a waterless serum formulated with powerful actives and efficacious botanicals each at a minimum of 6%.
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Pesticides and preservatives are utilized to destroy living bacteria, not knowing the difference between good and bad flora. We limit your skin’s exposure to them.
CURRENT PRACTICES
Most traditional formulas use conventionally grown botanical ingredients that are exposed to some of the most potent pesticide residues and are preserved with the goal of maximizing long shelf-lives (average period-after-opening date: 12 months).
> While preservatives are essential in extending shelf-life and ensuring the safety of water-based products, they are often used in excess.
> Conventional pesticides have the potential to deplete your skin’s microbiome over time, harm farmers, soil, habitats, and other organisms, and also lead to the production of greenhouse gases.
SWEET CHEMISTRY PRODUCTS
Our botanical oils and extracts are not only certified organic and free from the most harmful pesticides but smartly protected and preserved without the need for excessive preservatives.
> This gives you the convenience of shelf-life (6 month period-after-opening) without compromising your microbiome or putting soil, habitat, or farmer health, at risk.
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Our packaging uses 87% less plastic and protects our actives so you get the performance you expect.
TRADITIONAL PACKAGING
Most airless bottles used for skincare are made from plastic. While the beauty industry is making an effort to use alternative materials such as glass, most glass used for beauty products tends to be heavier in weight than plastic packaging and therefore usually not the more eco-friendly choice.
> At the same time, relying too much on plastic packaging is damaging to our environment, oceans, and habitats.SWEET CHEMISTRY PRODUCTS
Meet the world’s first ultra-light glass airless bottle: Aside from the small plastic pump/overcap, our packaging is crafted from lightweight Italian glass, so light in fact, some of our customers have even mistaken it for plastic.
> Using 87% less plastic by mass than plastic airless bottles, our packaging helps us control our carbon emissions. They have also been shown to protect actives from oxidation more effectively than plastic or glass dropper bottles.
> We also designed our bottle so you are able to dispense every last drop of product.
Let’s Get Clinical
Independent clinical studies show that Matrikynes® deliver statistically significant improvements for multiple skin types and tones.
Improve skin barrier repair within 1 hour
Skin barrier repair improves 12% faster and 61% better within 1 hour, rapidly supporting skin’s restorative and refortifying abilities.
Increase skin density (collagen)
Skin density increases by 8.3% within 4 weeks, signaling skin to restore collagen and strengthen itself for a revitalized, youthful appearance.
Visibly reduces global fine lines & wrinkles
Fine lines and deep wrinkles are visibly reduced by 3.7% and skin looks noticeably smoother in only 4 weeks.
Increase skin hydration
Essential skin hydration increases significantly by 8.4% within 4 weeks and continues to build with regular use.
Improve skin barrier function
Skin barrier function improves dramatically by 5.8% in just 4 weeks, enabling skin to ‘act efficiently’ like younger, healthy skin.
Improve the appearance of hyperpigmentation & age spots
Hyperpigmentation/age spots are reduced by 3.6% within 4 weeks for more even skin tone and brighter complexion.
Cause no irritation and minimal sensitization
Occlusive repeated insult patch test was performed with Matrikynes® (neat), and no irritation or sensitization to was observed.
Visibly reduce redness
Redness is significantly reduced and skin tone as well as texture are improved.
What Our Community Thinks
Bioengineering Is at the Heart, Lungs & Skin of What We Do
Aside from being our award-winning formulas’ defining ingredient, Matrikynes® are used in clinical applications in regenerative medicine: They were born from innovative research in organ tissue repair by Dr. John O’Neill, originally from Columbia University's Laboratory for Stem Cells and Tissue Engineering, and his team at our parent company Xylyx Bio.
Beyond creating this novel peptide technology we use in our products exclusively, Xylyx Bio develops biomaterials and organ support systems: From lifesaving surgical lung sealants, to advanced platform technologies for organ rehabilitation and transplantation, to helping discover novel cancer and fibrosis treatments.
8 Years of Research & Over $8 Million In NIH Government Funding
Originally used in clinical applications to repair lung tissue, Matrikynes® are a proprietary combination of potent bioactive natural matrikine signal peptides. Matrikine signal peptides have been shown to improve the structure, function, and appearance of skin.
• Increased Cellular Renewal By 336%
• Reduced Wound Size By 421%
• Increased Regenerative Gene Expression By 316%
The Origins of Matrikynes®
These matrikine signal peptides are derived from extracellular matrix (ECM), the essential, life-sustaining substance that surrounds every cell in your body. Without extracellular matrix, life could not exist.
ECM gives cells the ability to organize and communicate which signals your skin to regenerate and repair.
Finding Healing in the Extracellular Matrix
Skin tissue is made up of water, cells, and an essential substance called extracellular matrix (ECM). The ECM is made up of structural proteins you might be familiar with such as collagen, elastin, laminin, and fibronectin, and contain components such as hyaluronic acid, ceramides, squalene, glycosaminoglycans, cholesterol, minerals, epidermal growth factors, and many other substances that are essential to the human body.
Skin ECM supports cell function and helps cells communicate, repair, and regenerate, which is essential for maintaining a healthy skin barrier. Over time, due to factors like sun exposure, stress, and aging, skin ECM starts to break down, resulting in a progressive loss of important ECM components like collagen, which eventually leads to the development of fine lines and wrinkles.
While traditional formulas use synthetic/artificial peptides to help rebuild collagen with some success, we also formulate with our proprietary, highly bioavailable matrix-derived polypeptides, which are derived from ethically-sourced, USDA-compliant, upcycled bovine bones the food industry would otherwise discard.
What makes bone the source of choice for our polypeptides is that it is a tissue with natural regenerative properties and an unparalleled reparative capacity.
Unlocking Unparalleled
Skin Health
To create Sweet Chemistry Matrikynes®, our scientists break down extracellular matrix proteins into skin penetrable peptide fragments using a process known as proteolysis.
As one of the defining actives in our products, these proprietary Matrikynes® polypeptides act as a signal that tells your skin to produce more collagen which helps increase skin density, and thereby reduce the appearance of fine lines/wrinkles. Matrikynes® also help maintain and improve overall skin texture, and firmness, as well as target redness, hyperpigmentation, and skin barrier concerns.
Rather than a marketing "complex", our technology ingredient has been assessed and granted its own internationally recognized INCI name and is patent-pending. This allows us to be the only brand to harness this technology in the world.
“Without ECM, Life Could Not Exist.
Plants Would Not Grow Tall, and Animals
Could neither Swim, nor Walk, nor Fly.”
- WH LEWIS, LIFE SCIENCES AND CELL BIOLOGY, 1922
The Beauty of Belonging
As a beauty brand, we’re committed to challenging rigid ideals and creating a space where everyone, especially young people, can confidently express who they are—beyond looks. That’s why we donate 1% of sales to support the next generation of scientists and artists, and spotlight our parent company Xylyx’s groundbreaking research in organ rehabilitation—because beauty goes beyond skin deep.
iResearch
The iResearch Institute is a study program for high school students without access to advanced science education - founded by the godmother of science research, Dr. Serena McCalla.
YoungArts
YoungArts identifies exceptional young artists, amplifies their potential, and invests in their lifelong creative freedom. It envisions a world that embraces artists as vital to our humanity.
Xylyx Bio
Our parent company, Xylyx Bio, is a biomedical technology leader in tissue engineering and organ rehabilitation, dedicated to eliminating the organ donor waitlist.