Pathological Remodeling of Distal Lung Matrix in End-Stage Cystic Fibrosis Patients
Stella Lee
Manifestations of cystic fibrosis, although well-characterized in the proximal airways, are understudied in the distal lung. Characterization of the cystic fibrosis lung 'matrisome' (matrix proteome) has not been previously described, and could help identify biomarkers and inform therapeutic strategies.