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Theranostic Methodology for Ex Vivo Donor Lung Rehabilitation

Theranostic Methodology for Ex Vivo Donor Lung Rehabilitation

This resource reports a methodology for therapeutic and diagnostic (“theranostic”) intervention to rehabilitate donor lungs during cross-circulation. 
Mechanisms and Strategies for Organ Recovery

Mechanisms and Strategies for Organ Recovery

This Review summarizes the biological mechanisms of cellular injury, perfusate modifications and mechanistic approaches for reinstating circulation, and offers perspectives on the future of organ and whole-body recovery.
Lung Rehabilitation Using Xenogeneic Cross-Circulation Does Not Lead to Hyperacute Rejection in a Human Lung Transplantation Model

Lung Rehabilitation Using Xenogeneic Cross-Circulation Does Not Lead to Hyperacute Rejection in a Human Lung Transplantation Model

Access to life-saving lung transplantation remains limited by a shortage of donor organs. We have previously described rehabilitation of discarded human donor lungs to a quality suitable for transplantation using cross-circulation of whole blood between...
Characterization of Porcine Immunoglobulin Deposition in Human Livers Recovered Using a Xenogeneic Cross-Circulation

Characterization of Porcine Immunoglobulin Deposition in Human Livers Recovered Using a Xenogeneic Cross-Circulation

The shortage of donor organs highlights the need for innovative techniques to improve organ recovery and rehabilitation.
Xylyx Bio Awarded $2.45M NIH SBIR Grant from NIDDK to Facilitate Development of Effective Drugs for Fibrotic Liver Disease

Xylyx Bio Awarded $2.45M NIH SBIR Grant from NIDDK to Facilitate Development of Effective Drugs for Fibrotic Liver Disease

Award supports the development of a cell-based assay platform to help scientists discover and test drug candidates for liver fibrosis
The Farmer Behind the Formula: Alf and Lexa From Alaska Ocean Farms

The Farmer Behind the Formula: Alf and Lexa From Alaska Ocean Farms

Alf Pryor and Lexa Meyer of Alaska Ocean Farms share their amazing story and the processes behind sustainable kelp farming in the Gulf of Alaska. Learn about the challenges they've overcome, how they produce their...
Xylyx Bio Awarded $2.26M NIH SBIR Grant from National Cancer Institute

Xylyx Bio Awarded $2.26M NIH SBIR Grant from National Cancer Institute

  Award supports development of a pre-clinical cell-based assay platform to help scientists discover and test drug candidates for metastatic breast cancer
Guide to Extracellular Matrices (and How to Avoid Common Problems)

Guide to Extracellular Matrices (and How to Avoid Common Problems)

An integral part of mimicking the microenvironment of specific cell types in a tissue culture dish is the use of extracellular matrices (ECM). 
Xylyx Bio Announces Exclusive License Agreement with Vanderbilt University for Donor Organ Rehabilitation Asset

Xylyx Bio Announces Exclusive License Agreement with Vanderbilt University for Donor Organ Rehabilitation Asset

Xylyx Bio, a regenerative medicine company developing innovative solutions for tissue and organ repair, today announced entry into an exclusive license agreement with Vanderbilt University for the rights to a xenogeneic cross-circulation platform that restores damaged donor...