Independent clinical study results validate Matrikynes® efficacy in reversing common signs of skin damage and aging, including reduction of lines and wrinkles.

Improved approaches to expanding the pool of donor lungs suitable for transplantation are critically needed for the growing population with end-stage lung disease.

Xenogeneic cross-circulation (XC) is an experimental method for ex vivo organ support and recovery that could expand the pool of donor lungs suitable for transplantation. The objective of this study was to establish and validate...

Study demonstrates that a novel technique for regenerating donor lungs can increase the number of organs available for life-saving transplantation

The extracellular matrix (ECM) is a complex mixture surrounding live cells, composed of fibrous proteins that provide structure and physical support, and other types of molecules that function in signaling and cell health.

Despite increasing use of machine perfusion as an organ preservation and rescue technique in liver transplantation, significant organ shortages and waitlist mortality highlight a continuing need for improved organ recovery methods. 

Manifestations of cystic fibrosis, although well-characterized in the proximal airways, are understudied in the distal lung. Characterization of the cystic fibrosis lung 'matrisome' (matrix proteome) has not been previously described, and could help identify biomarkers...

Researchers at the University of Illinois applied Xylyx Bio's IN SITE™ Metastasis Kit to evaluate a cancer therapeutic.

Xenogeneic cross-circulation is a promising method to recover marginal lungs. It may be more advantageous than EVLP but could introduce risks of zoonotic infections and sensitization to xenoantigens.