The number of available donor organs limits lung transplantation, the only lifesaving therapy for the increasing population of patients with end-stage lung disease. 

To study cells in a more physiologically relevant environment, scientists are turning increasingly to three-dimensional cultures.

Extracorporeal cross-circulation between lungs enables the extended support of recipient lungs and the recovery of injured lungs in a swine model.

The shortage of transplantable donor organs has profound consequences, especially for patients with end-stage lung disease, for which transplantation remains the only definitive treatment. Although advances in ex vivo lung perfusion have enabled the evaluation and reconditioning...