Injured and unusable lungs were restored with respirators and pig blood.  The procedure one day may increase the supply of organs for transplant.

Here we demonstrate that acutely injured human lungs declined for transplantation, including a lung that failed to recover on EVLP, can be recovered by cross-circulation of whole blood between explanted human lungs and a Yorkshire...

Unusual method could increase the supply of lungs available for transplantation.

The IN SITE™ Metastasis Kit provides key features of the cancer microenvironment to increase predictiveness and improve decision making in development of anti-cancer drugs

Lung remains the least-utilized solid organ for transplantation. Efforts to recover donor lungs with reversible injuries using ex vivo perfusion systems are limited to <24 hours of support. Here, we demonstrate the feasibility of extending normothermic extracorporeal...

While the primary benefit of 3D cell cultures—greater resemblance to in vivo conditions than their 2D counterparts—is undoubtedly valuable in physiological research, 3D cultures are still more difficult to use compared to 2D cultures. But...

Fibrosis-specific substrates provide a disease-relevant in-vitro testing platform to inform decision-making in early-stage drug discovery

Xylyx Bio to focus on accelerating the standardization and commercialization of tissue-specific extracellular matrix biomaterials for regenerative medicine and tissue engineering

By overlooking physiologic components of the extracellular environment, researchers risk obtaining misleading or irreproducible results in the critical early stages of drug discovery and development.